Scanning Probe Microscope - SPM - capable of measuring the following characteristics of sample surface: a) 3D topography, to measure roughness and step height; b) Lateral Force Microscopy - LFM - to measure frictional properties; c) Magnetic Force Microscopy - MFM - to map magnetic domain; d) current sensing Atomic Force Microscopy - AFM - to measure conductivity distribution; e) IV curve; f) Electrostatic Force Microscopy - EFM - to qualitatively measure local static charge domain and charge carrier density; g) Kelvin Force Microscopy - KFM - to quantitatively measure surface potential; h) Piezoresponse Force Microscopy - PFM - to measure electromechanical properties of piezoelectric and ferroelectric materials; i) Force Spectroscopy, to measure polarity and strength of the interaction between AFM tip and sample; j) Scanning Tunneling Microscopy - STM - to measure topography using tunneling current.
Sample - thin films, nanoparticles and nanowire with maximum structure height of 8 um. Nanoparticles and nanowires must to be fixed on flat substrate.

Scanning Probe Microscope - SPM - capable of measuring the following characteristics of surface sample: a) 3D topography; b) surface roughness; c) magnetic and electrical properties; d) topography imaging mode (atmospheric/liquid environment) - 3D image; and e) step height. It can also perform Lateral Force Microscopy - LFM -to measure the frictional properties; and Magnetic Force Microscopy - MFM - to map magnetic domain.
Sample - thin films, nanoparticles and nanowires with maximum structure height of 8 um. Nanoparticles and nanowires must to be fixed on flat substrate.

The Axis Supra system from Kratos in our facility is the state of the art electron spectrometer combining X-ray photoelectron spectroscopy (XPS), micro XPS and imaging XPS. The Axis Supra system is equipped with a monochromatic X-ray source and a dual Al-Mg anode. High collection efficiency and high spatial resolution is provided by a magnetic lens. For low collection angles an electrostatic lens can be used, either independently or in combination with the magnetic lens. Hemispherical analyser (HSA) provides both high energy resolution and high sensitivity for micro spectroscopy with spatial resolution <15 um. With addition of the spherical mirror analyser (SMA), real time chemical state images down to 1 um spatial resolution can be obtained in the parallel imaging mode.
The Axis supra is equipped also with an Argon cluster Gun for depth profiling.
The Axis supra has an UPS (ultra violet photoelectron spectroscopy) capablity to measure the work function of the materials.

The Dimension Icon SPM is a member of the Scanning Probe Microscope Family. It uses a very sharp tip (around 10 nm) to perform the surface measurement. By recording the interaction between the tip and sample surface, the 3D topography and other physical properties such as frictional coefficient and distribution of magnetic domains can be measured.
Main functions: ScanAsyst in Air; ScanAsyst in Liquid; Contact Mode; Tapping Mode; Force Spectroscopy; Force Volume; Magnetic Force Microscopy; Piezoresponse Force Microscopy; PeakForce QNM; KPFM Mode .

Nano Test Vantage is a flexible modular materials testing system. It employs a hard tip whose mechanical properties are known (frequently made of a very hard material like diamond) to measure sample deformation under small load. The load displacement data can be used to analyze mechanical properties of thin films and other solid surfaces, such as hardness, modulus, toughness, fracture, fatigue, wear and fretting.
Main functions: Mechanical property analysis on surface; Indentation test; Scanning test; Scrach test; Impulse/Impact test; Fretting test
Sample - thin films and bulk with smooth surface.

The Axis Ultra DLD system from Kratos in our facility is the state of the art electron spectrometer combining X-ray photoelectron spectroscopy (XPS), micro XPS and imaging XPS. The Axis Ultra DLD system is equipped with monochromatic X-ray source and dual Al-Mg anode. High collection efficiency and high spatial resolution is provided by a magnetic lens. For low collection angles an electrostatic lens can be used, either independently or in combination with the magnetic lens. Hemispherical analyser (HSA) provides both high energy resolution and high sensitivity for micro spectroscopy with spatial resolution <15 um. With addition of the spherical mirror analyser (SMA), real time chemical state images down to 3 um spatial resolution can be obtained in the parallel imaging mode.
Samples - powders or films with a dimension of 1.5 X 1.5 cm, (>20 mg), and no oil content.

Measures specific surface area (BET), pore volume, and very accurate pore size distribution, of ultamicroporous (0.35 - 0.7 nm, with high precision and high resolution), (microporous (0.7nm - 2nm), mesoporous (2nm - 50nm) and low surface area materials by probing the activated surface of the sample with gases such as Nitrogen, Argon, CO2 or others and measuring the adsorbed gas volume at fixed bath temperature (i.e. liquid nitrogen, liquid argon, ice bath) and increasing static pressure ranging from 0.001 umHg up to 760 mmHg. The relative pressure data start in the range of 10^-09 p/p0 where ultramicropores start filling.
Vapor adsorption option is also available for saturated, unsaturated hydrocarbons, and aromatic rings. Other kinds of vapors need to be discussed with lab scientists.
Samples - solids, powders or polymers. Quantity to be discussed with lab scientists.

THUNDER Imager 3D Live Cell is designed for imaging of cell culture assays. It allows a clear view of details, even deep within an intact sample, in real time without out-of- focus blur. This performance advantage is achieved with a new opto-digital method created by Leica Microsystems called Computational Clearing. THUNDER Imager help to maintain optimal physiological conditions by minimizing photobleaching, providing high- performance imaging and high-throughput of data leading to better workflow efficiency and statistics.

Reason T20 Dual head #1

Trapped Ion Mobility Spectrometry (TIMS) adds 4th dimension of separation. TIMS is first and foremost a separation technique in gas phase, which resolves sample complexity with an added dimension of separation in addition to UHPLC and mass spectrometry, increasing peak capacity and confidence in compound characterization.
The instrument is focused on metabolomics/lipidomics studies.

timsTOF Pro LCMS setup, including timsTOF Pro (1900000) + nanoElute (1832734)+ column toaster (1862996)+ CaptiveSpray nanobooster (1820410) + 2 x high performance Aurora columns (1867781).
The timsTOF Pro system comes with a dual-TIMS analyzer is optimized for high-speed shotgun proteomics. Its unique geometry allows incoming ions to be accumulated in parallel in the first section, and for ions to be released dependent on their mobility from the second section of the dual-TIMS analyzer. This results in nearly 100% duty cycle, making this parallel accumulation serial fragmentation technique (PASEF) perfectly suited for nanoflow LC-MS analysis of enzymatically digested complex protein mixtures.
Measurements in both, MS and PASEF mode. Includes Apollo II ion funnel ESI source, dual trapped ion mobility analyzer for parallel accumulation, high performance quadrupole, high transmission collision cell for CID, temperature controlled and compensated TOF analyzer, electronics, integrated syringe pump, Data System with 5GS/s digitizer and 24'' LCD monitor, Compass Software for HPLC and MS control, data acquisition and processing.
nanoElute is an ideal companion to any Bruker’s UHR-Q-TOF’s instruments.
nanoElute comes with a unique valve design and novel instrument configuration designed for trouble-free operation and ease-of-use along with top performance:
• Unique valve design allows seamless column switch for direct load or pre-concentration architecture via software.
• Instant ExpertiseTM methods have been extended to the LC method to generate tailor-made instrument methods. Additionally, inline MS calibration enables high-quality mass data generation.
• Precise diagnostics to detect leaks and blockages that are crucial for retention time stability and peak area reproducibility
• Built-in quality control and scheduling of preventative maintenance allow biologists to focus on the biology and leave maintenance of the LC to the intelligent diagnostic system

The LabChip® GX Touch™ nucleic acid analyzer’s microfluidic technology generates reproducible, high-resolution data and is optimal for
1-NGS library preparation (smear and fragment analysis) and quality control
2-RNA and DNA fragment analysis (including cell-free (cfDNA), FFPE, liquid biopsy, and PCR-free samples)
3-Quantitation and qualification for CRISPR fragment analysis
4-Agarose gel workflows
Sample type: DNA, RNA, NGS libraries

The MiSeq sequencing System facilitates the research with a wide range of sequencing applications. It is capable of automated paired-end reads and up to 15 Gb per run, delivering over 600 bases of sequence data per read. Applications include (but not limited to) targeted gene, small genome, and amplicon sequencing, 16S metagenomics.
The read length available is 2 x 300 bp, run time is 60h
Sample: any Illumina compatible library

The JPK NanoWizard® V combines high spatio-temporal resolution with a large scan area, flexible experiment design, and out-standing integration with advanced optical microscope systems. The automated setup, alignment, and re-adjustment of system parameters opens new possibilities for long-term, self-regulating experiment series.

The Asylum Research MFP-3D is a member of the Scanning Probe Microscope Family. It uses a very sharp tip (around 10 nm) to perform the surface measurement. By recording the interaction between the tip and sample surface, the 3D topography and other physical properties such as frictional coefficient and distribution of magnetic domains can be measured.
Main functions : ScanAsyst in Air; ScanAsyst in Liquid; Contact Mode; Tapping Mode; Force Spectroscopy; Force Volume; Magnetic Force Microscopy; Piezoresponse Force Microscopy; PeakForce QNM; PeakForce TUNA; KPFM Mode; Data Cube Mode; Temperature controlled AFM

The Dimension Icon SPM is a member of the Scanning Probe Microscope Family. It uses a very sharp tip (around 10 nm) to perform the surface measurement. By recording the interaction between the tip and sample surface, the 3D topography and other physical properties such as frictional coefficient and distribution of magnetic domains can be measured.
Main functions: ScanAsyst in Air; ScanAsyst in Liquid; Contact Mode; Tapping Mode; Force Spectroscopy; Force Volume; Magnetic Force Microscopy; Piezoresponse Force Microscopy; PeakForce QNM; PeakForce TUNA; KPFM Mode; Data Cube Mode; Temperature controlled AFM.

The ID-X Tribrid system is a fully integrated Ultra High Performance Liquid Chromatography coupled with high resolution/accurate mass (HRAM) Orbitrap mass analyzer.

Thermo Scientific™ Helios™ 5 UX DualBeam scanning electron microscope incorporates a suite of state-of-the-art technologies that enables simple and consistent high-resolution S/TEM and atom probe tomography (APT) sample preparation, as well as the highest-quality subsurface and 3D characterization.
#SEM #FIB #Etching #metrology

As a small milling machine, the SRM-20 offers compact size and powerful functionality for the Production of realistic parts and prototypes. For users looking for advanced milling capabilities without the need for expert operating skills, the SRM-20 is the easiest and most precise CNC mill in its class.

Fast and precise large-scale 3D printing is finally accessible in one compact package
With the BigRep STUDIO, we introduce a workhorse printer that brings a new dimension to large-scale 3D printing. The industrial-grade quality machine has a print volume of 500 mm x 1000 mm x 500 mm that enables continuous printing of large objects in a space-saving package.
The dual extruder equipped with two 0.6 mm hot ends has been specially designed for speed and precision. The direct-drive all-metal hot end allows for printing of a larger variety of high-performance filaments.
The BigRep STUDIO is optimal for premium large-scale 3D print projects and has been specifically designed for speed and precision. Delivering high-quality results around the clock, it is an ideal size for all working and production environments.
As winner of the prestigious 2018 German Innovation Award, the STUDIO is the ideal German-engineered 3D printer for professionals across industries to bring their innovative designs to life.
Specifications
Manufacturer BigRep GmbH Model BigRep STUDIO
Berlin / Germany Version 08/2017
Dimensions [X:Y:Z ] 1693 x 1056 x 1506 mm Weight Printer 350 kg
Min. Layer
Resolution
100 μm Extruder Dual extruder
Max. Layer
Resolution
400 μm Nozzle 0.6 mm diameter
Brass
Printing Technology FFF 3D Print Surface Polyimid
Build Volume Single
Extrusion [X:Y:Z]
1060 x 515 x 505 mm Heating
Strategy
Heated print
surface
Build Volume Dual
Extrusion [X:Y:Z]
1060 x 483 x 500 mm Extruder
Temperature
Max. 240° C
XY Position
Repeatability
100 μm Print Bed
Temperature
Ca. 60-70°C
Z Position
Repeatability
100 μm AC Input 208-240V 1 or 2
AC 50/60Hz, 16A
Filament Diameter 2.75 – 3 mm NC-Language G-Code
Printing Materials PLA, PETG, PRO HT,
PRO HS
Ambient Operating
Temperature
+15°C … +35°C
Firmware Smoothieware